Changes in impact of HLA class I allele expression on HIV-1 plasma virus loads at a population level over time.

Abstract excerpt

HLA class I allele types have differential impacts on the level of the pVL and outcome of HIV-1 infection. While accumulations of CTL escape mutations at population levels have been reported, their actual impact on the level of the pVL remains unknown. In this study HLA class I types from 141 untreated, chronically HIV-1 infected Japanese patients diagnosed from 1995-2007 were determined, and the associations...

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• Share to CD4 Lymphocyte Count
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