Article
Mps1 promotes chromosome meiotic chromosome biorientation through Dam1.
Molecular biology of the cell - 15 Feb 2018
Meyer Régis E, Brown Jamin, Beck Lindsay, Dawson Dean S
Abstract excerpt
In budding yeast meiosis, homologous chromosomes become linked by chiasmata and then move back and forth on the spindle until they are bioriented, with the kinetochores of the partners attached to microtubules from opposite spindle poles. Certain mutations in the conserved kinase, Mps1, result in catastrophic meiotic segregation errors but mild mitotic defects. We tested whether Dam1, a known substrate of Mps1,...
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