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Article

The multiple roles of mps1 in Drosophila female meiosis.

PLoS genetics - 1 Jul 2007

Gilliland William D, Hughes Stacie E, Cotitta Jeffrey L, Takeo Satomi, Xiang Youbin, Hawley R Scott

Abstract excerpt

The Drosophila gene ald encodes the fly ortholog of mps1, a conserved kinetochore-associated protein kinase required for the meiotic and mitotic spindle assembly checkpoints. Using live imaging, we demonstrate that oocytes lacking Ald/Mps1 (hereafter referred to as Ald) protein enter anaphase I immediately upon completing spindle formation, in a fashion that does not allow sufficient time for nonexchange homologs...

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Identifiers

PMID: 17630834
DOI: 10.1371/journal.pgen.0030113
PMCID: PMC1914070

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Source receipt: pubmed, retrieved 7 Sept 2026.

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