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Article

Mps1p regulates meiotic spindle pole body duplication in addition to having novel roles during sporulation.

Molecular biology of the cell - 1 Oct 2000

Straight P D, Giddings T H, Winey M

Abstract excerpt

Sporulation in yeast requires that a modified form of chromosome segregation be coupled to the development of a specialized cell type, a process akin to gametogenesis. Mps1p is a dual-specificity protein kinase essential for spindle pole body (SPB) duplication and required for the spindle assembly checkpoint in mitotically dividing cells. Four conditional mutant alleles of MPS1 disrupt sporulation, producing two...

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Source

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Identifiers

PMID: 11029053
DOI: 10.1091/mbc.11.10.3525
PMCID: PMC15011

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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