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Article

Mps1 phosphorylation of Dam1 couples kinetochores to microtubule plus ends at metaphase.

Current biology : CB - 8 Aug 2006

Shimogawa Michelle M, Graczyk Beth, Gardner Melissa K, Francis Susan E, White Erin A, Ess Michael, Molk Jeffrey N, Ruse Cristian, Niessen Sherry, Yates John R, Muller Eric G D, Bloom Kerry, Odde David J, Davis Trisha N

Abstract excerpt

BACKGROUND: Duplicated chromosomes are equally segregated to daughter cells by a bipolar mitotic spindle during cell division. By metaphase, sister chromatids are coupled to microtubule (MT) plus ends from opposite poles of the bipolar spindle via kinetochores. Here we describe a phosphorylation event that promotes the coupling of kinetochores to microtubule plus ends. RESULTS: Dam1 is a kinetochore component...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 16890524
DOI: 10.1016/j.cub.2006.06.063
PMCID: PMC1762913

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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