Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Use of a Sibling Subtraction Method for Identifying Causal Mutations in Caenorhabditis elegans by Whole-Genome Sequencing.

G3 (Bethesda, Md.) - 2 Feb 2018

Joseph Braveen B, Blouin Nicolas A, Fay David S

Abstract excerpt

Whole-genome sequencing (WGS) is an indispensable tool for identifying causal mutations obtained from genetic screens. To reduce the number of causal mutation candidates typically uncovered by WGS, Caenorhabditis elegans researchers have developed several strategies. One involves crossing N2-background mutants to the polymorphic Hawaiian (HA) strain, which can be used to simultaneously identify mutant strain...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Animals, Genetically Modified
Share to Caenorhabditis elegans

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Caenorhabditis elegans Proteins

Share to Chromosome Mapping

Share to Gene Expression Regulation

Share to Genes, Helminth

Share to Mutagenesis

Share to Whole Genome Sequencing

Source

Open in PubMed Open full text

Identifiers

PMID: 29237702
DOI: 10.1534/g3.117.300135
PMCID: PMC5919755

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Use of a Sibling Subtraction Method for Identifying Causal Mutations in Caenorhabditis elegans by Whole-Genome Sequencing.PMID 29237702Read ↗

MIP-MAP: High-Throughput Mapping of Caenorhabditis elegans Temperature-Sensitive Mutants via Molecular Inversion Probes.Semantic proximity Read ↗

Mapping Challenging Mutations by Whole-Genome Sequencing.Semantic proximity Read ↗

Rapid and Efficient Identification of Caenorhabditis elegans Legacy Mutations Using Hawaiian SNP-Based Mapping and Whole-Genome Sequencing.Semantic proximity Read ↗

Fast genetic mapping using insertion-deletion polymorphisms in Caenorhabditis elegans.Semantic proximity Read ↗

Whole genome sequencing and the transformation of C. elegans forward genetics.Semantic proximity Read ↗

A Genetic Interaction Screening Approach in C. elegans.Semantic proximity Read ↗

Rapid high resolution single nucleotide polymorphism-comparative genome hybridization mapping in Caenorhabditis elegans.Semantic proximity Read ↗

Identification of suppressors of mbk-2/DYRK by whole-genome sequencing.Semantic proximity Read ↗

Caenorhabditis elegans mutant allele identification by whole-genome sequencing.Semantic proximity Read ↗

C. elegans mutant identification with a one-step whole-genome-sequencing and SNP mapping strategy.Semantic proximity Read ↗

Mutation Mapping and Identification by Whole-Genome Sequencing.Semantic proximity Read ↗

Use of SNPs to determine the breakpoints of complex deficiencies, facilitating gene mapping in Caenorhabditis elegans.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.