Article
A Genetic Interaction Screening Approach in C. elegans.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2021
Calarco John A
Abstract excerpt
Genetic interaction screens have played a critical role in better understanding epistasis and functional relationships among genes. These screens have been conducted at multiple scales, ranging from testing pairwise interactions genome-wide in yeast and bacteria, to more focused screens in multicellular organisms and cultured cells. Here, I describe a strategy that facilitates genetic interaction screens with...
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