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Article

Whole genome sequencing and the transformation of C. elegans forward genetics.

Methods (San Diego, Calif.) - 1 Aug 2014

Hu Patrick J

Abstract excerpt

Forward genetics has been an undeniably powerful approach in Caenorhabditis elegans and other model organisms. However, the trek from mutant isolation to identification of the causative molecular lesion can be time-consuming and fraught with obstacles. This has changed with the advent of whole genome sequencing (WGS). The widespread availability of high-throughput sequencing technology, coupled with the...

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PMID: 24874788
DOI: 10.1016/j.ymeth.2014.05.008

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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