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Article

Identification of suppressors of mbk-2/DYRK by whole-genome sequencing.

G3 (Bethesda, Md.) - 19 Feb 2014

Wang Yuemeng, Wang Jennifer T, Rasoloson Dominique, Stitzel Michael L, O' Connell Kevin F, Smith Harold E, Seydoux Geraldine

Abstract excerpt

Screening for suppressor mutations is a powerful method to isolate genes that function in a common pathway or process. Because suppressor mutations often do not have phenotypes on their own, cloning of suppressor loci can be challenging. A method combining whole-genome sequencing (WGS) and single nucleotide polymorphism (SNP) mapping (WGS/SNP mapping) was developed to identify mutations with visible phenotypes in...

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PMID: 24347622
DOI: 10.1534/g3.113.009126
PMCID: PMC3931558

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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