Article
C. elegans mutant identification with a one-step whole-genome-sequencing and SNP mapping strategy.
PloS one - 8 Nov 2010
Doitsidou Maria, Poole Richard J, Sarin Sumeet, Bigelow Henry, Hobert Oliver
Abstract excerpt
Whole-genome sequencing (WGS) is becoming a fast and cost-effective method to pinpoint molecular lesions in mutagenized genetic model systems, such as Caenorhabditis elegans. As mutagenized strains contain a significant mutational load, it is often still necessary to map mutations to a chromosoma...
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