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Mapping Challenging Mutations by Whole-Genome Sequencing.

G3 (Bethesda, Md.) - 3 May 2016

Smith Harold E, Fabritius Amy S, Jaramillo-Lambert Aimee, Golden Andy

Abstract excerpt

Whole-genome sequencing provides a rapid and powerful method for identifying mutations on a global scale, and has spurred a renewed enthusiasm for classical genetic screens in model organisms. The most commonly characterized category of mutation consists of monogenic, recessive traits, due to their genetic tractability. Therefore, most of the mapping methods for mutation identification by whole-genome sequencing...

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Identifiers

PMID: 26945029
DOI: 10.1534/g3.116.028316
PMCID: PMC4856081

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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