Article
Impaired Protein Quality Control During Left Ventricular Remodeling in Mice With Cardiac Restricted Overexpression of Tumor Necrosis Factor.
Circulation. Heart failure - 1 Dec 2017
Hartupee Justin, Szalai Gabor D, Wang Wei, Ma Xiucui, Diwan Abhinav, Mann Douglas L
Abstract excerpt
BACKGROUND: Sustained inflammation in the heart is sufficient to provoke left ventricular dysfunction and left ventricular remodeling. Although inflammation has been linked to many of the biological changes responsible for adverse left ventricular remodeling, the relationship between inflammation and protein quality control in the heart is not well understood. METHODS AND RESULTS: To study the relationship...
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