Article
Hyperubiquitination of proteins in dilated cardiomyopathy.
Proteomics - 1 Feb 2003
Weekes John, Morrison Karen, Mullen Anthony, Wait Robin, Barton Paul, Dunn Michael J
Abstract excerpt
Protein degradation by the ubiquitin-proteasome pathway plays an important role in a variety of fundamental cellular processes, including cell cycle regulation, transcription, antigen processing and muscle remodelling. Research into disorders associated with the ubiquitin-proteasome system has been mainly in the field of neurodegenerative diseases. It is however becoming increasingly apparent that defects in the...
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