Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Characterization of mice carrying a conditional TEAD1 allele.

Genesis (New York, N.Y. : 2000) - 1 Dec 2017

Wen Tong, Yin Qin, Yu Luyi, Hu Guoqing, Liu Jinhua, Zhang Wei, Huang Liang, Su Huabo, Wang Menghong, Zhou Jiliang

Abstract excerpt

The Hippo- yes-associated protein (YAP) pathway is essential for controlling organ size and tumorigenesis. Previous studies have demonstrated that the primary outcome of YAP signaling in the nucleus is achieved by interaction with the transcription factor TEA domain transcription factor (TEAD1). The YAP/TEAD1 complex binds to DNA element and regulates the expression of genes involved in cell growth. However,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adaptor Proteins, Signal Transducing
Share to Cell Cycle Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Embryonic Development

Share to Gene Expression Regulation, Developmental

Share to Genes, Lethal

Share to Integrases

Share to Phosphoproteins

Share to YAP-Signaling Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 29193599
DOI: 10.1002/dvg.23085
PMCID: PMC5735023

Genes

TEAD1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Characterization of mice carrying a conditional TEAD1 allele.PMID 29193599Read ↗

Redundant roles of Tead1 and Tead2 in notochord development and the regulation of cell proliferation and survival.Semantic proximity Read ↗

An improved TEAD dominant-negative protein inhibitor to study Hippo YAP1/TAZ-dependent transcriptionSemantic proximity Read ↗

Generation of the floxed allele of the SIP1 (Smad-interacting protein 1) gene for Cre-mediated conditional knockout in the mouse.Semantic proximity Read ↗

Conditional knockout mouse models of cancer.Semantic proximity Read ↗

Generation of a Wt1 conditional deletion, nuclear red fluorescent protein reporter allele in the mouse.Semantic proximity Read ↗

Hippo vs. Crab: tissue-specific functions of the mammalian Hippo pathway.Semantic proximity Read ↗

Histone methyltransferase Dot1L plays a role in postembryonic development in Xenopus tropicalis.Semantic proximity Read ↗

An allelic series for studying the mouse Thoc1 gene.Semantic proximity Read ↗

Murine models for the study of thyroid gland development.Semantic proximity Read ↗

Zebrafish mutants and TEAD reporters reveal essential functions for Yap and Taz in posterior cardinal vein development.Semantic proximity Read ↗

Generation and characterization of mice for conditional inactivation of Zeb1.Semantic proximity Read ↗

The Wilms tumor suppressor gene wt1 is required for development of the spleen.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.