Article
Murine models for the study of thyroid gland development.
Endocrine development - 1 Jan 2007
Felice Mario De, Lauro Roberto Di
Abstract excerpt
Gene targeting technology has allowed the generation of mouse mutants which lack specific genes. These mice represent a valuable tool for identifying the in vivo functions of proteins and for dissecting the pathways that control the development and differentiation of the numerous structures of the body. What we know about thyroid morphogenesis is largely due to studies on murine models generated in gene-targeting...
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