Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Conditional knockout mouse models of cancer.

Cold Spring Harbor protocols - 1 Dec 2014

Deng Chu-Xia

Abstract excerpt

In 2007, three scientists, Drs. Mario R. Capecchi, Martin J. Evans, and Oliver Smithies, received the Nobel Prize in Physiology or Medicine for their contributions of introducing specific gene modifications into mice. This technology, commonly referred to as gene targeting or knockout, has proven to be a powerful means for precisely manipulating the mammalian genome and has generated great impacts on virtually...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Breast Neoplasms
Share to Disease Models, Animal
Share to Mice, Knockout

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mutation

Share to Neoplasm Proteins

Share to Neoplasms

Source

Identifiers

PMID: 25447286
DOI: 10.1101/pdb.top074393

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Conditional knockout mouse models of cancer.PMID 25447286Read ↗

Conditional mouse models of sporadic cancer.Semantic proximity Read ↗

New approaches for modelling cancer mechanisms in the mouseSemantic proximity Read ↗

Genetically modified mouse models in cancer studies.Semantic proximity Read ↗

Mouse models of inherited cancer syndromes.Semantic proximity Read ↗

Mouse models of BRCA1 and BRCA2 deficiency: past lessons, current understanding and future prospects.Semantic proximity Read ↗

Genetically engineered knock-in and conditional knock-in mouse models of cancer.Semantic proximity Read ↗

Mouse Models of CancerSemantic proximity Read ↗

Cancer modeling in the modern era: progress and challenges.Semantic proximity Read ↗

Strategies to achieve conditional gene mutation in mice.Semantic proximity Read ↗

Conditional knockout mice.Semantic proximity Read ↗

Insights into cancer from transgenic mouse models.Semantic proximity Read ↗

Overview of transgenic and gene knockout mice.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.