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Article

The primary role of zebrafish nanog is in extra-embryonic tissue.

Development (Cambridge, England) - 9 Jan 2018

Gagnon James A, Obbad Kamal, Schier Alexander F

Abstract excerpt

The role of the zebrafish transcription factor Nanog has been controversial. It has been suggested that Nanog is primarily required for the proper formation of the extra-embryonic yolk syncytial layer (YSL) and only indirectly regulates gene expression in embryonic cells. In an alternative scenario, Nanog has been proposed to directly regulate transcription in embryonic cells during zygotic genome activation. To...

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Identifiers

PMID: 29180571
DOI: 10.1242/dev.147793
PMCID: PMC5825865

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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