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Article

ENCoRE: an efficient software for CRISPR screens identifies new players in extrinsic apoptosis.

BMC genomics - 25 Nov 2017

Trümbach Dietrich, Pfeiffer Susanne, Poppe Manuel, Scherb Hagen, Doll Sebastian, Wurst Wolfgang, Schick Joel A

Abstract excerpt

BACKGROUND: As CRISPR/Cas9 mediated screens with pooled guide libraries in somatic cells become increasingly established, an unmet need for rapid and accurate companion informatics tools has emerged. We have developed a lightweight and efficient software to easily manipulate large raw next generation sequencing datasets derived from such screens into informative relational context with graphical support. The...

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Identifiers

PMID: 29178829
DOI: 10.1186/s12864-017-4285-2
PMCID: PMC5702081

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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