Article

Benchmark data and software for assessing genome-wide CRISPR-Cas9 screening pipelines

2022-09-25

Abstract excerpt

<h4>ABSTRACT</h4> Genome-wide recessive genetic screens using lentiviral CRISPR-guide RNA libraries are widely performed in mammalian cells to functionally characterise individual genes and for the discovery of new anti-cancer therapeutic targets. As the effectiveness of such powerful and precise tools for cancer pharmacogenomic is emerging, reference datasets for their quality assessment and the validation of th...

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Literature Corpus work: ee889a14-fefe-5910-a42a-8496672f417e
DOI: 10.1101/2022.09.23.509258

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