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Role of epithelial to mesenchymal transition associated genes in mammary gland regeneration and breast tumorigenesis

15 Nov 2017

Abstract excerpt

Previous studies have proposed that epithelial to mesenchymal transition (EMT) in breast cancer cells regulates metastasis, stem cell properties and chemo-resistance; most studies were based on in vitro culture of cell lines and mouse transgenic cancer models. However, the identity and function of cells expressing EMT-associated genes in normal murine mammary gland homeostasis and human breast cancer still...

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PMID: 29162812
DOI: 10.1038/s41467-017-01666-2

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