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Article

Epithelial-Mesenchymal Transition Programs and Cancer Stem Cell Phenotypes: Mediators of Breast Cancer Therapy Resistance.

Molecular cancer research : MCR - 1 Sept 2020

Gooding Alex J, Schiemann William P

Abstract excerpt

Epithelial-mesenchymal transition (EMT) programs play essential functions in normal morphogenesis and organogenesis, including that occurring during mammary gland development and glandular regeneration. Historically, EMT programs were believed to reflect a loss of epithelial gene expression signatures and morphologies that give way to those associated with mesenchymal cells and their enhanced migratory and...

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Identifiers

PMID: 32503922
DOI: 10.1158/1541-7786.MCR-20-0067
PMCID: PMC7483945

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