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Article

Mouse mammary stem cells express prognostic markers for triple-negative breast cancer.

Breast cancer research : BCR - 4 Mar 2015

Soady Kelly J, Kendrick Howard, Gao Qiong, Tutt Andrew, Zvelebil Marketa, Ordonez Liliana D, Quist Jelmar, Tan David Wei-Min, Isacke Clare M, Grigoriadis Anita, Smalley Matthew J

Abstract excerpt

INTRODUCTION: Triple-negative breast cancer (TNBC) is a heterogeneous group of tumours in which chemotherapy, the current mainstay of systemic treatment, is often initially beneficial but with a high risk of relapse and metastasis. There is currently no means of predicting which TNBC will relapse. We tested the hypothesis that the biological properties of normal stem cells are re-activated in tumour metastasis...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Epithelial Cells

Share to Mammary Glands, Animal

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Identifiers

PMID: 25849541
DOI: 10.1186/s13058-015-0539-6
PMCID: PMC4381533

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