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Human Primary Breast Cancer Stem Cells Are Characterized by Epithelial-Mesenchymal Plasticity

11 Feb 2021

Abstract excerpt

Triple-negative breast cancer (TNBC) is one of the most aggressive subtypes of breast cancer, with only limited treatment options available. Recently, cancer stem cells (CSCs) have emerged as the potential drivers of tumor progression due to their ability to both self-renew and give rise to differentiated progeny. The CSC state has been linked to the process of epithelial-mesenchymal transition (EMT) and to the...

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PMID: 33670400
DOI: 10.3390/ijms22041808

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