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Article

Phenotypic plasticity and epithelial-mesenchymal transitions in cancer and normal stem cells?

International journal of cancer - 15 Nov 2011

Scheel Christina, Weinberg Robert A

Abstract excerpt

Cancer stem cells (CSCs) are similar to normal stem cells in their ability to self-renew and to generate large populations of more differentiated descendants. In contrast to the hierarchical organization that is presumed to be the prevalent mode of normal tissue homeostasis, phenotypic plasticity allows cancer cells to dynamically enter into and exit from stem-cell states. The epithelial-mesenchymal transition...

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Identifiers

PMID: 21792896
DOI: 10.1002/ijc.26311
PMCID: PMC3357895

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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