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Article

Family-based tests for associating haplotypes with general phenotype data: Improving the FBAT-haplotype algorithm.

Genetic epidemiology - 1 Feb 2018

Hecker Julian, Xu Xin, Townes F William, Loehlein Fier Heide, Corcoran Chris, Laird Nan, Lange Christoph

Abstract excerpt

For family-based association studies, Horvath et al. proposed an algorithm for the association analysis between haplotypes and arbitrary phenotypes when the phase of the haplotypes is unknown, that is, genotype data is given. Their approach to haplotype analysis maintains the original features of the TDT/FBAT-approach, that is, complete robustness against genetic confounding and misspecification of the phenotype....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 29159827
DOI: 10.1002/gepi.22094
PMCID: PMC5774664

Genes

APOE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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