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Article

Identification of risk-related haplotypes with the use of multiple SNPs from nuclear families.

American journal of human genetics - 1 Jul 2007

Shi Min, Umbach David M, Weinberg Clarice R

Abstract excerpt

Family-based association studies offer robustness to population stratification and can provide insight into maternally mediated and parent-of-origin effects. Usually, such studies investigate multiple markers covering a gene or chromosomal region of interest. We propose a simple and general method to test the association of a disease trait with multiple, possibly linked SNP markers and, subsequently, to nominate...

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Share to Genetic Markers
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 17564963
DOI: 10.1086/518670
PMCID: PMC1950926

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