Article
A novel approach for haplotype-based association analysis using family data.
BMC bioinformatics - 18 Jan 2010
Chen Yixuan, Li Xin, Li Jing
Abstract excerpt
BACKGROUND: Haplotype-based approaches have been extensively studied for case-control association mapping in recent years. It has been shown that haplotype methods can provide more consistent results comparing to single-locus based approaches, especially in cases where causal variants are not typed. Improved power has been observed by clustering similar or rare haplotypes into groups to reduce the degrees of...
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