Article
Human-induced pluripotent stem cells: potential for neurodegenerative diseases.
Human molecular genetics - 15 Sept 2014
Ross Christopher A, Akimov Sergey S
Abstract excerpt
The cell biology of human neurodegenerative diseases has been difficult to study till recently. The development of human induced pluripotent stem cell (iPSC) models has greatly enhanced our ability to model disease in human cells. Methods have recently been improved, including increasing reprogramming efficiency, introducing non-viral and non-integrating methods of cell reprogramming, and using novel gene editing...
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