Article
Enhancement of invadopodia activity in glioma cells by sublethal doses of irradiation and temozolomide.
Journal of neurosurgery - 1 Sept 2018
Mao Leon, Whitehead Clarissa A, Paradiso Lucia, Kaye Andrew H, Morokoff Andrew P, Luwor Rodney B, Stylli Stanley S
Abstract excerpt
OBJECTIVE Glioblastoma is the most common primary central nervous system tumor in adults. These tumors are highly invasive and infiltrative and result in tumor recurrence as well as an extremely poor patient prognosis. The current standard of care involves surgery, radiotherapy, and chemotherapy. However, previous studies have suggested that glioblastoma cells that survive treatment are potentially more invasive....
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