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Article

Membrane Proteome Analysis of Glioblastoma Cell Invasion

8 Apr 2015

Abstract excerpt

Glioblastoma multiforme (GBM) tumor invasion is facilitated by cell migration and degradation of the extracellular matrix. Invadopodia are actin-rich structures that protrude from the plasma membrane in direct contact with the extracellular matrix and are proposed to participate in epithelial-mesenchymal transition. We characterized the invasiveness of 9 established GBM cell lines using an invadopodia assay and...

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PMID: 25853691
DOI: 10.1097/nen.0000000000000187

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