Article

Cleavage of the vascular matrix attracts glioblastoma cells to infiltrate the brain parenchyma

2024-08-06

Abstract excerpt

<h4>Background</h4> Glioblastoma is a highly aggressive brain cancer and, unlike many other cancers types, the median survival for patients after treatment (14.6 months) has barely improved in the last 20 years. Infiltrative growth into the surrounding brain parenchyma facilitates tumor recurrence and ultimately the death of the patient - novel therapies targeting this process are desperately needed. Lysyl oxidas...

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Literature Corpus work: 6acae4db-0099-5e09-a451-15445192c365
DOI: 10.1101/2024.08.02.606279

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