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Article

Invadopodia in context

6 Mar 2014

Abstract excerpt

Invadopodia are dynamic protrusions in motile tumor cells whose function is to degrade extracellular matrix so that cells can enter into new environments. Invadopodia are specifically identified by microscopy as proteolytic invasive protrusions containing TKS5 and cortactin. The increasing complexity in models for the study of invadopodia, including engineered 3D environments, explants, or animal models in vivo,...

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PMID: 24713806
DOI: 10.4161/cam.28349

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