Cost of migration: invasion of malignant gliomas and implications for treatment.

Abstract excerpt

Tumors of glial origin consist of a core mass and a penumbra of invasive, single cells, decreasing in numbers towards the periphery and still detectable several centimeters away from the core lesion. Several decades ago, the diffuse nature of malignant gliomas was recognized by neurosurgeons when super-radical resections using hemispherectomies failed to eradicate these tumors. Local invasiveness eventually leads...

Topics

• Brain Neoplasms
• Cell Movement
• Glioma
• Humans
• Neoplasm Invasiveness
• Phenotype