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Article

Genomic analysis of atypical fibroxanthoma.

PloS one - 1 Jan 2017

Lai Kevin, Harwood Catherine A, Purdie Karin J, Proby Charlotte M, Leigh Irene M, Ravi Namita, Mully Thaddeus W, Brooks Lionel, Sandoval Priscilla M, Rosenblum Michael D, Arron Sarah T

Abstract excerpt

Atypical fibroxanthoma (AFX), is a rare type of skin cancer affecting older individuals with sun damaged skin. Since there is limited genomic information about AFX, our study seeks to improve the understanding of AFX through whole-exome and RNA sequencing of 8 matched tumor-normal samples. AFX is a highly mutated malignancy with recurrent mutations in a number of genes, including COL11A1, ERBB4, CSMD3, and FAT1....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Open in PubMed Open full text

Identifiers

PMID: 29141020
DOI: 10.1371/journal.pone.0188272
PMCID: PMC5687749

Genes

CSMD3
ERBB4
FAT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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