Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genome-wide association study of actinic keratosis identifies new susceptibility loci implicated in pigmentation and immune regulation pathways.

Communications biology - 21 Apr 2022

Kim Yuhree, Yin Jie, Huang Hailiang, Jorgenson Eric, Choquet Hélène, Asgari Maryam M

Abstract excerpt

Actinic keratosis (AK) is a common precancerous cutaneous neoplasm that arises on chronically sun-exposed skin. AK susceptibility has a moderate genetic component, and although a few susceptibility loci have been identified, including IRF4, TYR, and MC1R, additional loci have yet to be discovered. We conducted a genome-wide association study of AK in non-Hispanic white participants of the Genetic Epidemiology...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Forkhead Transcription Factors
Share to Genetic Predisposition to Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genome-Wide Association Study

Share to Polymorphism, Single Nucleotide

Share to Repressor Proteins

Share to Skin Neoplasms

Source

Open in PubMed Open full text

Identifiers

PMID: 35449187
DOI: 10.1038/s42003-022-03301-3
PMCID: PMC9023580

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genome-wide association study of actinic keratosis identifies new susceptibility loci implicated in pigmentation and immune regulation pathways.PMID 35449187Read ↗

IRF4, MC1R and TYR genes are risk factors for actinic keratosis independent of skin color.Semantic proximity Read ↗

Pigmentation-Independent Susceptibility Loci for Actinic Keratosis Highlighted by Compound Heterozygosity Analysis.Semantic proximity Read ↗

The Genomic Landscape of Actinic Keratosis.Semantic proximity Read ↗

Genomic analysis of atypical fibroxanthoma.Semantic proximity Read ↗

A multi-phenotype analysis reveals 19 novel susceptibility loci for basal cell carcinoma and 15 for squamous cell carcinomaSemantic proximity Read ↗

A multi-phenotype analysis reveals 19 susceptibility loci for basal cell carcinoma and 15 for squamous cell carcinomaSemantic proximity Read ↗

Genome-wide association study identifies novel susceptibility loci for cutaneous squamous cell carcinoma.Semantic proximity Read ↗

Genome-wide association study identifies novel alleles associated with risk of cutaneous basal cell carcinoma and squamous cell carcinoma.Semantic proximity Read ↗

From actinic keratosis to cutaneous squamous cell carcinoma: the key pathogenesis and treatmentsSemantic proximity Read ↗

Multi-ancestry genome-wide meta-analysis identifies novel basal cell carcinoma loci and shared genetic effects with squamous cell carcinoma.Semantic proximity Read ↗

Genome-wide association study identifies 14 novel risk alleles associated with basal cell carcinoma.Semantic proximity Read ↗

p63 and PITX1 sustain a pre-invasive malignant keratinocyte population in squamous cell carcinoma precursorsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.