Systems genetic analysis of brown adipose tissue function.

doi:10.1152/physiolgenomics.00091.2017

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Article

Systems genetic analysis of brown adipose tissue function.

Physiological genomics - 1 Jan 2018

Pravenec Michal, Saba Laura M, Zídek Václav, Landa Vladimír, Mlejnek Petr, Šilhavý Jan, Šimáková Miroslava, Strnad Hynek, Trnovská Jaroslava, Škop Vojtěch, Hüttl Martina, Marková Irena, Oliyarnyk Olena, Malínská Hana, Kazdová Ludmila, Smith Harry, Tabakoff Boris

Abstract excerpt

Brown adipose tissue (BAT) has been suggested to play an important role in lipid and glucose metabolism in rodents and possibly also in humans. In the current study, we used genetic and correlation analyses in the BXH/HXB recombinant inbred (RI) strains, derived from Brown Norway (BN) and spontaneously hypertensive rats (SHR), to identify genetic determinants of BAT function. Linkage analyses revealed a...

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Identifiers

PMID: 29127223
DOI: 10.1152/physiolgenomics.00091.2017
PMCID: PMC5866413

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.