Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Integrated genomic approaches to identification of candidate genes underlying metabolic and cardiovascular phenotypes in the spontaneously hypertensive rat.

Physiological genomics - 7 Nov 2011

Morrissey Catherine, Grieve Ian C, Heinig Matthias, Atanur Santosh, Petretto Enrico, Pravenec Michal, Hubner Norbert, Aitman Timothy J

Abstract excerpt

The spontaneously hypertensive rat (SHR) is a widely used rodent model of hypertension and metabolic syndrome. Previously we identified thousands of cis-regulated expression quantitative trait loci (eQTLs) across multiple tissues using a panel of rat recombinant inbred (RI) strains derived from Brown Norway and SHR progenitors. These cis-eQTLs represent potential susceptibility loci underlying physiological and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to 5' Untranslated Regions
Share to Cardiovascular Diseases

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Gene Expression Profiling

Share to Genomics

Share to Oligonucleotide Array Sequence Analysis

Share to Quantitative Trait Loci

Share to Rats, Inbred SHR

Share to Reproducibility of Results

Source

Open in PubMed Open full text

Identifiers

PMID: 21846806
DOI: 10.1152/physiolgenomics.00210.2010
PMCID: PMC3217321

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Integrated genomic approaches to identification of candidate genes underlying metabolic and cardiovascular phenotypes in the spontaneously hypertensive rat.PMID 21846806Read ↗

Quantitative trait analysis in a panel of recombinant inbred rat strainsSemantic proximity Read ↗

The genome sequence of the spontaneously hypertensive rat: Analysis and functional significance.Semantic proximity Read ↗

Integrative genomic analysis of blood pressure and related phenotypes in rats.Semantic proximity Read ↗

Modelling genetic and genomic interactions underlying gene expression and complex traitsSemantic proximity Read ↗

Genetic analysis of complex cardiovascular traits in the spontaneously hypertensive rat.Semantic proximity Read ↗

Functional characterisation of the genomes of rat models of human diseasesSemantic proximity Read ↗

Integrating genetic and gene expression data: application to cardiovascular and metabolic traits in miceSemantic proximity Read ↗

Functional genomics in hypertension.Semantic proximity Read ↗

Physiogenomic resources for rat models of heart, lung and blood disorders.Semantic proximity Read ↗

Physiogenomic strategies and resources to associate genes with rat models of heart, lung and blood disorders.Semantic proximity Read ↗

Genome-wide co-expression analysis in multiple tissues.Semantic proximity Read ↗

Conserved properties of genetic architecture of renal and fat transcriptomes in rat models of insulin resistanceSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.