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Article

Identification of genes and networks driving cardiovascular and metabolic phenotypes in a mouse F2 intercross.

PloS one - 14 Dec 2010

Derry Jonathan M J, Zhong Hua, Molony Cliona, MacNeil Doug, Guhathakurta Debraj, Zhang Bin, Mudgett John, Small Kersten, El Fertak Lahcen, Guimond Alain, Selloum Mohammed, Zhao Wenqing, Champy Marie France, Monassier Laurent, Vogt Tom, Cully Doris, Kasarskis Andrew, Schadt Eric E

Abstract excerpt

To identify the genes and pathways that underlie cardiovascular and metabolic phenotypes we performed an integrated analysis of a mouse C57BL/6JxA/J F2 (B6AF2) cross by relating genome-wide gene expression data from adipose, kidney, and liver tissues to physiological endpoints measured in the pop...

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Identifiers

PMID: 21179467
DOI: 10.1371/journal.pone.0014319
PMCID: PMC3001864

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-21179467-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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