Article

Transcriptome-wide Analyses of Adipose Tissue in Outbred Rats Reveal Genetic Regulatory Mechanisms Relevant for Human Obesity

2022-03-24

Abstract excerpt

<h4>ABSTRACT</h4> Transcriptomic analysis in metabolically active tissues allows a systems genetics approach to identify causal genes and networks involved in metabolic disease. Outbred heterogeneous stock (HS) rats are used for genetic mapping of complex traits, but to-date, a systems genetics analysis of metabolic tissues has not been done. We investigated whether adiposity-associated genes and gene co-expressi...

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Literature Corpus work: 2a6496e8-28bf-5106-a187-84f469d582a4
DOI: 10.1101/2022.03.24.485632

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