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Article

Single Nucleotide Polymorphisms of Paclitaxel-induced Peripheral Sensory Neuropathy in Chinese Han Population.

Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae - 30 Oct 2017

Dou Xue-Lin, Mai Yu-Lin, Sun Zhao, Wang Ying-Yi, Shao Ya-Juan, Cheng Yue-Juan, Zhou Na, Luo Fei, Zhang Biao, Bai Chun-Mei, Ma Shui-Qing

Abstract excerpt

Objective To study the single nucleotide polymorphisms (SNPs)that predict a patient's risk of grade 2-3 paclitaxel-induced peripheral sensory neuropathy (PSN) in Chinese Han populations.Methods Totally 216 patients received paclitaxel in Peking Union Medical College Hospital from May 2014 to December 2016 were enrolled.DNA was isolated from peripheral blood.Genotyping for eight candidate SNPs was performed on...

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PMID: 29125099
DOI: 10.3881/j.issn.1000-503X.2017.05.001

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LIMK2

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