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Article

Pharmacoethnicity in Paclitaxel-Induced Sensory Peripheral Neuropathy.

Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Oct 2015

Komatsu Masaaki, Wheeler Heather E, Chung Suyoun, Low Siew-Kee, Wing Claudia, Delaney Shannon M, Gorsic Lidija K, Takahashi Atsushi, Kubo Michiaki, Kroetz Deanna L, Zhang Wei, Nakamura Yusuke, Dolan M Eileen

Abstract excerpt

PURPOSE: Paclitaxel is used worldwide in the treatment of breast, lung, ovarian, and other cancers. Sensory peripheral neuropathy is an associated adverse effect that cannot be predicted, prevented, or mitigated. To better understand the contribution of germline genetic variation to paclitaxel-induced peripheral neuropathy, we undertook an integrative approach that combines genome-wide association study (GWAS)...

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Source

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Identifiers

PMID: 26015512
DOI: 10.1158/1078-0432.CCR-15-0133
PMCID: PMC4592389

Genes

AIPL1
BCR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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