Article
The evolutionarily conserved factor Sus1/ENY2 plays a role in telomere length maintenance.
Current genetics - 1 Jun 2018
Galán Amparo, García-Oliver Encar, Nuño-Cabanes Carme, Rubinstein Linda, Kupiec Martin, Rodríguez-Navarro Susana
Abstract excerpt
Sus1 is a conserved protein involved in histone H2B de-ubiquitination and mRNA export from the nucleus in eukaryotes. Previous studies implicated Sus1 partners in genome integrity including telomere homeostasis. However, the implication of Sus1 in telomere maintenance remains largely unknown. In this study, we found that yeast Sus1 interacts physically and genetically with factors involved in telomere maintenance...
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