Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Telomeric circles are abundant in the stn1-M1 mutant that maintains its telomeres through recombination.

Nucleic acids research - 1 Jan 2010

Basenko Evelina Y, Cesare Anthony J, Iyer Shilpa, Griffith Jack D, McEachern Michael J

Abstract excerpt

Some human cancers maintain their telomeres using the alternative lengthening of telomeres (ALT) mechanism; a process thought to involve recombination. Different types of recombinational telomere elongation pathways have been identified in yeasts. In senescing yeast telomerase deletion (ter1-Delta) mutants with very short telomeres, it has been hypothesized that copying a tiny telomeric circle (t-circle) by a...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to DNA, Circular
Share to Electrophoresis, Gel, Two-Dimensional

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Kluyveromyces

Share to Mutation

Share to Recombination, Genetic

Share to Telomere

Source

Open in PubMed Open full text

Identifiers

PMID: 19858100
DOI: 10.1093/nar/gkp814
PMCID: PMC2800209

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Telomeric circles are abundant in the stn1-M1 mutant that maintains its telomeres through recombination.PMID 19858100Read ↗

Maintenance of very long telomeres by recombination in the Kluyveromyces lactis stn1-M1 mutant involves extreme telomeric turnover, telomeric circles, and concerted telomeric amplification.Semantic proximity Read ↗

Recombination at long mutant telomeres produces tiny single- and double-stranded telomeric circles.Semantic proximity Read ↗

A mutation in the STN1 gene triggers an alternative lengthening of telomere-like runaway recombinational telomere elongation and rapid deletion in yeast.Semantic proximity Read ↗

Extrachromosomal telomere DNA derived from excessive strand displacementsSemantic proximity Read ↗

Unusual Telomeric DNAs in Human Telomerase-Negative Immortalized CellsSemantic proximity Read ↗

Telomere loops and homologous recombination-dependent telomeric circles in a Kluyveromyces lactis telomere mutant strain.Semantic proximity Read ↗

Extrachromosomal Telomeres Derived from Excessive Strand DisplacementsSemantic proximity Read ↗

Human CST Has Independent Functions during Telomere Duplex Replication and C-Strand Fill-InSemantic proximity Read ↗

Recombinational telomere elongation promoted by DNA circles.Semantic proximity Read ↗

Distinct mechanisms underlying extrachromosomal telomere DNA generation in ALT cancersSemantic proximity Read ↗

Distinct mechanisms underlying extrachromosomal telomere DNA generation in ALT cancersSemantic proximity Read ↗

Telomeric DNA in ALT Cells Is Characterized by Free Telomeric Circles and Heterogeneous t-LoopsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.