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Article

Genetic association study identified a 20 kb regulatory element in WLS associated with osteoporosis and bone mineral density in Han Chinese.

Scientific reports - 20 Oct 2017

Zhang Dangfeng, Ge Zhaohui, Ma Xin, Zhi Liqiang, Zhang Yunzhi, Wu Xueyuan, Yao Shuxin, Ma Wei

Abstract excerpt

Previous studies have linked the WNT pathway and human skeleton formation; therefore, genes related to WNT might contribute to the onset and development of osteoporosis. In this study, we investigated the potential genetic association of WLS, which encodes an important mediator in the WNT pathway, with osteoporosis and its related quantitative traits in a sample of 6,620 individuals from Han Chinese population. A...

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Identifiers

PMID: 29057911
DOI: 10.1038/s41598-017-13932-w
PMCID: PMC5651806

Genes

WLS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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