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Article

Intermedin reduces neointima formation by regulating vascular smooth muscle cell phenotype via cAMP/PKA pathway.

Atherosclerosis - 1 Nov 2017

Zhu Qing, Ni Xian-Qiang, Lu Wei-Wei, Zhang Jin-Sheng, Ren Jin-Ling, Wu Di, Chen Yao, Zhang Lin-Shuang, Yu Yan-Rong, Tang Chao-Shu, Qi Yong-Fen

Abstract excerpt

BACKGROUND AND AIMS: Vascular smooth muscle cell (VSMC) dedifferentiation contributes to neointima formation, which results in various vascular disorders. Intermedin (IMD), a cardiovascular paracrine/autocrine polypeptide, is involved in maintaining circulatory homeostasis. However, whether IMD protects against neointima formation remains largely unknown. The purpose of this study is to investigate the role of...

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PMID: 29053988
DOI: 10.1016/j.atherosclerosis.2017.10.011

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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