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Article

Intermedin1-53 Attenuates Abdominal Aortic Aneurysm by Inhibiting Oxidative Stress.

Arteriosclerosis, thrombosis, and vascular biology - 1 Nov 2016

Lu Wei-Wei, Jia Li-Xin, Ni Xian-Qiang, Zhao Lei, Chang Jin-Rui, Zhang Jin-Sheng, Hou Yue-Long, Zhu Yi, Guan You-Fei, Yu Yan-Rong, Du Jie, Tang Chao-Shu, Qi Yong-Fen

Abstract excerpt

OBJECTIVE: Oxidative stress plays a critical role in the development of abdominal aortic aneurysm (AAA). Intermedin (IMD) is a regulator of oxidative stress. Here, we investigated whether IMD reduces AAA by inhibiting oxidative stress. APPROACH AND RESULTS: In angiotensin II-induced ApoE-/- mouse and CaCl2-induced C57BL/6J mouse model of AAA, IMD1-53 significantly reduced the incidence of AAA and maximal aortic...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 27634835
DOI: 10.1161/ATVBAHA.116.307825

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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