Article
Fission yeast minichromosome loss mutants mis cause lethal aneuploidy and replication abnormality.
Molecular biology of the cell - 1 Oct 1994
Takahashi K, Yamada H, Yanagida M
Abstract excerpt
Precise chromosome transmission in cell division cycle is maintained by a number of genes. The attempt made in the present study was to isolate temperature-sensitive (ts) fission yeast mutants that display high loss rates of minichromosomes at permissive or semipermissive temperature (designated mis). By colony color assay of 539 ts strains that contain a minichromosome, we have identified 12 genetic loci...
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