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Article

A Computational Approach to Estimating Nondisjunction Frequency in Saccharomyces cerevisiae.

G3 (Bethesda, Md.) - 8 Jan 2016

Chu Daniel B, Burgess Sean M

Abstract excerpt

Errors segregating homologous chromosomes during meiosis result in aneuploid gametes and are the largest contributing factor to birth defects and spontaneous abortions in humans. Saccharomyces cerevisiae has long served as a model organism for studying the gene network supporting normal chromosome segregation. Measuring homolog nondisjunction frequencies is laborious, and involves dissecting thousands of tetrads...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 26747203
DOI: 10.1534/g3.115.024380
PMCID: PMC4777129

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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