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Article

Structural basis for regulation of the nucleo-cytoplasmic distribution of Bag6 by TRC35.

Proceedings of the National Academy of Sciences of the United States of America - 31 Oct 2017

Mock Jee-Young, Xu Yue, Ye Yihong, Clemons William M

Abstract excerpt

The metazoan protein BCL2-associated athanogene cochaperone 6 (Bag6) forms a hetero-trimeric complex with ubiquitin-like 4A and transmembrane domain recognition complex 35 (TRC35). This Bag6 complex is involved in tail-anchored protein targeting and various protein quality-control pathways in the cytosol as well as regulating transcription and histone methylation in the nucleus. Here we present a crystal...

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Identifiers

PMID: 29042515
DOI: 10.1073/pnas.1702940114
PMCID: PMC5676875

Genes

BCL2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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