Article
Subclassification of the RBCC/TRIM superfamily reveals a novel motif necessary for microtubule binding.
The Journal of biological chemistry - 31 Mar 2006
Short Kieran M, Cox Timothy C
Abstract excerpt
The biological significance of RBCC (N-terminal RING finger/B-box/coiled coil) proteins is increasingly being appreciated following demonstrated roles in disease pathogenesis, tumorigenesis, and retroviral protective activity. Found in all multicellular eukaryotes, RBCC proteins are involved in a vast array of intracellular functions; but as a general rule, they appear to function as part of large protein...
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